Low Dose NaltrexoneChronic Pain, Inflammation & Immune Support
What is Low Dose Naltrexone?
Low Dose Naltrexone (LDN) is a revolutionary approach to using naltrexone, typically prescribed at doses between 0.5mg to 4.5mg per day. At these microdoses, naltrexone acts completely differently than at standard doses, offering unique therapeutic benefits.
While naltrexone at standard doses (50mg) blocks opioid receptors to treat addiction, LDN at low doses briefly blocks these receptors, triggering your body to produce more natural endorphins and regulate immune responses.
LDN vs Standard Naltrexone
How LDN Works in Your Body
Understanding the science behind LDN's powerful effects on immune function and pain management.
1. Temporary Receptor Blocking
LDN briefly blocks opioid receptors for 2-4 hours, signaling your body that endorphin levels are low.
2. Endorphin Upregulation
Your body responds by producing more natural endorphins and enkephalins, creating a rebound effect.
3. Immune Modulation
Increased endorphins help regulate immune system function, reducing inflammation and supporting healing.
Key Mechanisms of Action
Neuroinflammation Reduction
LDN may suppress microglial cell activity in the brain and central nervous system, decreasing inflammatory cytokines.
- Reduced IL-1β and TNF-α
- Decreased microglial activation
- Enhanced neuroprotection
Immune System Balance
By modulating endorphin production, LDN may help restore immune function, reducing autoimmune responses while maintaining protective immunity.
- Th1/Th2 balance support
- Regulatory T-cell support
- Reduced autoimmune activity
Conditions LDN May Help
Research explores LDN across chronic conditions involving immune dysfunction and inflammation.
Fibromyalgia
Trials suggest pain reduction and improved quality of life in many patients using LDN.
Autoimmune Disorders
MS, RA, Lupus, and Crohn's disease reports indicate potential symptom improvements.
Chronic Fatigue Syndrome
Many patients report increased energy and reduced post-exertional symptoms.
Depression & Anxiety
Endorphin enhancement may support mood stabilization for some individuals.
Long COVID Symptoms
Emerging evidence suggests support for fatigue, brain fog, and inflammatory symptoms.
Chronic Pain & Inflammation
Non-addictive relief pathway via endorphin and inflammatory signaling.
LDN Dosing Calculator
Get personalized dosing recommendations based on your condition and weight. Always consult with your healthcare provider before starting LDN.
Patient Information
Dosing Recommendation
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Real Success Stories
Hear from patients whose lives have been transformed by Low Dose Naltrexone therapy through RecoverlyRX.
"After 8 years of fibromyalgia pain, LDN gave me my life back. Within 3 months, my pain decreased by 70% and I could sleep through the night again."
"My MS progression has slowed significantly since starting LDN. My fatigue is manageable and I haven't had a relapse in over a year."
"LDN has been a game-changer for my chronic fatigue. I went from barely functional to working full-time again. RecoverlyRX made it so easy to get started."
Patient Outcome Statistics
Clinical Case Studies
Detailed analysis of LDN treatment outcomes in real-world clinical settings.
Fibromyalgia Clinical Trial
Study Design
Randomized, double-blind, placebo-controlled trial with 31 fibromyalgia patients over 12 weeks.
Results
- • 57% reduction in daily pain scores
- • 30% improvement in sleep quality
- • Significant improvement in quality of life measures
Multiple Sclerosis Study
Study Design
40 patients with primary progressive MS treated with 4mg LDN daily for 6 months.
Results
- • 20% reduction in spasticity scores
- • Improved mental health quality of life
- • No serious adverse events reported
Why Choose RecoverlyRX for LDN?
We're the leading telehealth platform for LDN therapy, combining medical expertise with convenience and privacy.
LDN-Specialized Providers
Our physicians have extensive experience with LDN therapy and understand the unique needs of each condition.
- Board-certified physicians
- LDN training and certification
- Ongoing medical support
Precision Compounding
We partner with accredited compounding pharmacies to ensure consistent, high-quality LDN formulations.
- Custom dosing options
- Immediate-release capsules
- Quality testing guarantee
Comprehensive Support
From initial evaluation through ongoing treatment, we provide complete care coordination and monitoring.
- Regular follow-up appointments
- 24/7 support line
- Treatment optimization
RecoverlyRX vs Traditional Care
| Feature | RecoverlyRX | Traditional Clinic |
|---|---|---|
| Wait Time for Appointment | Same Day | 2-4 Weeks |
| LDN Experience | Specialized | Limited |
| Prescription Delivery | Direct to Home | Pharmacy Pickup |
| Ongoing Support | 24/7 Access | Office Hours Only |
Frequently Asked Questions
Get answers to common questions about LDN therapy and treatment with RecoverlyRX.
Still have questions?
Ready to Start Your LDN Journey?
Join thousands of patients who have found relief through Low Dose Naltrexone therapy. Get expert care from the comfort of your home.
Evaluation takes less than 15 minutes • HIPAA secure • Available in 45 states